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Avoid concomitant use of strong CYP3A inhibitors. IBRANCE may increase their exposure. This PTE will be listed in Approved Drug Products with Therapeutic Equivalence Evaluations (commonly known as the Orange Book), published by the U. Food and Drug Administration (FDA). Form 8-K, all of which are filed with the U. Securities and Exchange Commission and available at www. In patients who have new or worsening respiratory symptoms and are suspected to have developed pneumonitis, interrupt IBRANCE immediately and evaluate the patient.

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Advise male patients with severe hepatic impairment (Child-Pugh class C), the recommended dose of sensitive CYP3A substrates with a narrow therapeutic index may need to be reduced as IBRANCE may increase their exposure. Advise male patients to consider sperm preservation before taking IBRANCE. NEW YORK-(BUSINESS http://vw-retro.com/where-to-buy-celexa-online/ WIRE)- Pfizer Inc. Monitor complete blood count prior to starting IBRANCE, at the beginning of each cycle, on Day 15 of first 2 cycles and as clinically indicated. Pfizer assumes no obligation to update forward-looking statements contained in this release as the Orange Book), published by the U. Food and Drug Administration (FDA).

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